Therapeutic area

Acne

  • PRO gap analysis and competitor review in acne vulgaris
  • PRO development in acne vulgaris
  • Concept elicitation interviews in acne vulgaris to reach saturation
  • Observational psychometric validation study in acne vulgaris
  • Single item validation and user’s manual in acne vulgaris
  • Mixed method evaluation of an acne vulgaris measure – racial equivalence in non-Caucasion subjects using existing data
  • Medical writing for development and validation of a PRO in acne vulgaris
  • Clinical outcome assessments in acne scars
  • Literature research and content validation in acne scars
  • Analysis, reporting and patient interviews PRO in acne vulgaris
  • PRO instrument review in acne
  • Content validity testing of and regulatory support for use of the PRE-FACE in acne vulgaris
  • Linguistic validation and translation of the PRE-FACE

Acromegaly

  • Payer value proposition, payer value dossier and cost effectiveness model in acromegaly
  • Landscape analysis of acromegaly patient registries
  • Adequacy of the Acromegaly Quality of Life Questionnaire (AcroQoL) as an endpoint in acromegaly: endpoint review & strategic recommendations
  • Analysis of PRO data to support clinical trial dissemination activities in acromegaly
  • Consultancy to review acromegaly protocol
  • Exploratory analyses in acromegaly

Actinic keratosis

  • Literature review and stakeholder interviews on payer decision drivers in actinic keratosis
  • Statistical analysis and data interpretation from a multinational observational study in actinic keratosis
  • Manuscripts on a treatment for actinic keratosis
  • Patient diary study and analyses in actinic keratosis
  • Reporting on a patient diary study on adherence to topical treatment in actinic keratosis
  • Update of a dossier and development of a value story slide set to support affiliate teams in the value of an actinic keratosis product
  • Update to a core value dossier and value messages on actinic keratosis
  • Communication of PRO analysis from a phase III trial in actinic keratosis
  • Communication tool and materials on treatment in actinic keratosis
  • Publication summaries on treatment for actinic keratosis
  • Reimbursement dossier for a treatment in actinic keratosis
  • Use of PROs and ClinROs to build the best evidence and optimise market access for actinic keratosis

Adenomyosis

  • Development of disease-specific modules for adenomyosis

Alcohol dependence

  • Analysis and report generation on the medical environment for treatment of alcohol dependence
  • Supporting the development of a strategic ‘road map’ to support a publication on the alcohol dependent population
  • Definition of the alcohol dependent population in Europe
  • Literature review to understand the diagnosis, management and referral procedures for alcohol dependency in Japan
  • High level consultancy for a PRO endpoint strategy in alcohol dependence and obsessive compulsive disorder
  • Literature research and analysis on the economic and PRO burden of alcohol dependence

Allergic rhinitis

  • Structured review of medication adherence in allergic rhinitis compared with other treatments for chronic conditions
  • Review of PROs and development of a patient-reported screening tool in allergic rhinitis
  • Preference questionnaire on allergic rhinitis spray devices
  • Comparative preference trial with an experience questionnaire in allergic rhinitis
  • Focus groups assessing patient experience with nasal spray in allergic rhinitis, analysis of results and development of a report on concept elicitation and cognitive debriefing
  • Literature research and communications on the burden of nasal blockage in allergic rhinitis
  • Validation of the preference module of the Experience with Allergic Rhinitis Nasal Spray Questionnaire (EARNS-Q), with revisions to an FDA briefing document on the development and validation of the EARNS-Q experience and preference modules
  • Manuscript on the development of the EARNS-Q
  • Regulatory support for the EARNS-Q

Alopecia

  • Gap analysis of PROs for the use of a drug to grow darker and longer hair on the scalp
  • Conference poster on a gap analysis in alopecia
  • Development and validation of a photographic assessment and symptom measure in alopecia
  • Development of a symptom and impact PRO in alopecia
  • Development of a treatment satisfaction module for alopecia
  • Brief statistical analysis synthesis and interpretation (photo guide) in alopecia
  • Patient interviews for the development of alopecia-related PRO measures
  • Observational psychometric validation study in alopecia
  • Dossier on PRO measures in alopecia
  • PRO dossier for Subject Self-Assessment of Alopecia (SSAA)
  • Observational psychometric testing study in alopecia
  • Single item analysis in alopecia
  • Development of PRO and ClinRO instruments for alopecia totalis and alopecia universalis
  • Review and provide input into the development of a data analysis plan, validation study, drafts and final report of a randomized controlled trial on alopecia medicine
  • Conceptual equivalence testing of alopecia ePROs
  • Cognitive debriefing of the revised Subject Self-Assessment (SSA) and Hair Growth Questionnaire (HGQ) with patients with androgenic alopecia
  • Psychometric analyses and regulatory support in the development of PRO and ClinRO instruments for alopecia areata patchy,¬†universalis and totalis